Ozempic · Wegovy · Rybelsus
FDA-approved GLP-1 receptor agonist for type 2 diabetes and chronic weight management.
Semaglutide mimics the GLP-1 hormone, slowing gastric emptying and reducing appetite signals to the brain. It also improves insulin sensitivity and glucose-dependent insulin secretion. In clinical trials, participants lost an average of 15% of body weight over 68 weeks at the 2.4mg dose.
The following providers from our comparison carry this medication. Pricing and availability are verified May 2026.
Semaglutide mimics the GLP-1 hormone, which slows gastric emptying, reduces appetite signals to the brain, and improves insulin sensitivity. In clinical trials, participants lost an average of 15% of body weight over 68 weeks.
Ozempic (for type 2 diabetes) and Wegovy (for weight management) are the FDA-approved brand-name semaglutide products. Compounded semaglutide is also available during FDA shortage periods.
Semaglutide is administered as a once-weekly subcutaneous injection. Dosing typically starts at 0.25mg and is titrated up to 2.4mg for weight management (Wegovy) or 1.0mg for diabetes (Ozempic).
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